Boehringer Ingelheim Human Pharma Clinical Pipeline

Selection of projects in November 2024.

>15

Potential first-in-class assets anchor an innovation led portfolio

>10

New phase II and phase III start over the next 12-18 months

20

Potential new therapy approvals over the next seven years

50%

Of pipeline anchored in external collaborations (across research, pre-clinical and clinical portfolios)

Read more about Vicadrostat (BI 690517) + empagliflozin

Cardio-Renal-Metabolic

Chronic kidney disease

Aldosterone synthase inhibitor & SGLT2 inhibitor

Vicadrostat (BI 690517) & Empagliflozin

Read more about Vicadrostat (BI 690517) + empagliflozin

Cardio-Renal-Metabolic

Heart failure with preserved ejection fraction

Aldosterone synthase inhibitor & SGLT2 inhibitor

Vicadrostat (BI 690517) & Empagliflozin

Read more about Survodutide (BI 456906): GLP1/GCGR agonist | MASH

Cardio-Renal-Metabolic

Metabolic Dysfunction-Associated Steatohepatitis

GLP1/GCGR agonist

Survodutide (BI 456906)

Read more about Survodutide (BI 456906): GLP1/GCGR agonist | obesity

Cardio-Renal-Metabolic

Obesity

GLP1/GCGR agonist

Survodutide (BI 456906)

Read more about Iclepertin: GlyT1 inhibitor

Mental Health

Cognitive impairment associated with schizophrenia

GlyT1 inhibitor

Iclepertin (BI 425809)

Read more about CT-155: Prescription digital therapeutic

Mental Health

Schizophrenia

Prescription digital therapeutic

CT-155 (BI 3972080)

Read more about Zongertinib (BI 1810631): HER2 Tyrosine Kinase Inhibitor (TKI) | NSCLC

Oncology

Non-small cell lung cancer

HER2 TKI

Zongertinib (BI 1810631)

Read more about Nerandomilast (BI 1015550): PDE4B inhibitor

Respiratory

Idiopathic pulmonary fibrosis

PDE4B inhibitor

Nerandomilast (BI 1015550)

Read more about Nerandomilast (BI 1015550): PDE4B inhibitor

Respiratory

Progressive pulmonary fibrosis

PDE4B inhibitor

Nerandomilast (BI 1015550)

Read more about BI 764198: TRPC6 inhibitor

Cardio-Renal-Metabolic

Focal Segmental Glomerulosclerosis

TRPC6 inhibitor

BI 764198

Read more about BI 765845: Heart disease modulator | Myocardial infarction

Cardio-Renal-Metabolic

Myocardial infarction

Heart disease modulator

BI 765845

Read more about Spesolimab (BI 655130): IL36R antibody

Immunology

Hidradenitis suppurativa

IL36R antibody

Spesolimab (BI 655130)

Read more about Spesolimab (BI 655130): IL36R antibody

Immunology

Netherton syndrome

IL36R antibody

Spesolimab (BI 655130)

Read more about Spesolimab (BI 655130): IL36R antibody | PG

Immunology

Pyoderma gangrenosum

IL36R antibody

Spesolimab (BI 655130)

Read more about Nerandomilast (BI 1015550)

Immunology

Systemic Sclerosis

PDE4B inhibitor

Nerandomilast (BI 1015550)

Read more about Avenciguat (BI 685509): sGC activator | SSc

Immunology

Systemic sclerosis

sGC activator

Avenciguat (BI 685509)

Read more about BI 1569912

Mental Health

Major depressive disorder

NR2B NAM

BI 1569912

Read more about BI 764532: DLL3/CD3 T-cell engager | ep-NEC

Oncology

Extra-pulmonary neuroendocrine carcinoma

DLL3/CD3 T-cell engager

Obrixtamig (BI 764532)

Read more about BI 764532: DLL3/CD3 T-cell engager

Oncology

Small-cell lung cancer

DLL3/CD3 T-cell engager

Obrixtamig (BI 764532)

Read more about Ion channel inhibitor

Respiratory

Ion channel inhibitor

Read more about Lysophospholipase inhibitor

Respiratory

Idiopathic/progressive pulmonary fibrosis

Lysophospholipase inhibitor

BI 1819479

Read more about BI 1291583: CatC Inhibitor

Respiratory

Non-cystic fibrosis bronchiectasis

CatC inhibitor

BI 1291583

Read more about BI 764524: Sema3A antibody

Retinal Health

Diabetic retinopathy

Sema3A antibody

BI 764524

Read more about NPY2r agonist

Cardio-Renal-Metabolic

NPY2r agonist

Read more about Triple agonist peptide

Cardio-Renal-Metabolic

Triple agonist peptide

Read more about GLP-1/FGF21 agonist

Cardio-Renal-Metabolic

GLP-1/FGF21 agonist

Read more about Anti-fibrotic agent

Cardio-Renal-Metabolic

Anti-fibrotic agent

Read more about PD-1 antibody

Immunology

PD-1 antibody

Read more about TREM-1 Antibody

Immunology

TREM-1 antibody

Read more about Immunomodulator

Immunology

Immunomodulator

Read more about Digital Therapeutic

Mental Health

Prescription digital therapeutic

Read more about Glutamate receptor modulator

Mental Health

Glutamate receptor modulator

Read more about TRAILR2/CDH3 bispecific antibody

Oncology

TRAILR2/CDH3 bispecific antibody

Read more about Modified yersinia

Oncology

Modified yersinia

Read more about DLL3/CD3 T-cell engager

Oncology

DLL3/CD3 T-cell engager

Obrixtamig

Read more about CD137/FAP agonist

Oncology

CD137/FAP agonist

Read more about KRAS multi-inhibitor

Oncology

KRAS multi-inhibitor

Read more about KISIMA® Cancer Vaccine

Oncology

KISIMA® cancer vaccine

Read more about B7-H6/CD3 T-Cell Engager

Oncology

B7-H6/CD3 T-cell engager

Read more about HER2 TKI, Zongertinib

Oncology

HER2 TKI

Zongertinib

Read more about VSV-GP

Oncology

VSV-GP

Read more about Second generation STING agonist

Oncology

STING agonist (2nd generation)

Read more about SIRPα antagonist

Oncology

SIRPa antagonist

Read more about Ezabenlimab, PD-1 antibody

Oncology

PD-1 antibody

Ezabenlimab

Read more about IL11 antibody

Respiratory

IL11 antibody

Read more about Oxidase Inhibitor

Respiratory

Oxidase Inhibitor

Read more about Anti-fibrotic agent

Respiratory

Anti-fibrotic agent

Read more about C3-binding polypeptide

Retinal Health

C3-binding polypeptide

Read more about Vascular modulator

Retinal Health

Vascular modulator

Read more about Phospholipid modulator

Retinal Health

Phospholipid modulator